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USMLE-STEP-1United States Medical Licensing Step 1

847 Questions and Answers Experienced specialists selected 847 questions for this exam. All answers are verified to ensure correctness.

Last Updated May 14, 2024 Ace your exams with our consistently updated USMLE-STEP-1 exam dumps.

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Same Questions from the Latest Real Exam

USMLE-STEP-1 Online Practice Questions and Answers

Questions 1

A 7-year-old boy is examined by his pediatrician because of complaints of severe cramping pain in his legs whenever he rides his bike. He also expriences nausea and vomiting during these attacks. The child has noted that the severity of the cramps is most intense after dinners that include baked potatoes or pasta, and sometimes bread. Clinical studies undertaken following a treadmill test demonstrate myoglobinuria, hyperuricemia, and increased serum bilirubin. Which of the following enzyme deficiencies is associated with these clinical findings?

A. glucose-6-phosphatase

B. glycogen synthase

C. liver glycogen debranching enzyme

D. muscle phosphofructokinase

E. muscle phosphorylase

Show Answer
Questions 2

Amother has brought her 3-month-old baby to the pediatrician and indicates that the infant is lethargic and has poor suckling and seems uninterested in eating. In addition, the mother notes that the baby's diapers often smell like burnt sugar. This infant likely has a defect in which of the following enzymes?

A. branched-chain alpha-keto acid dehydrogenase

B. cystathionine synthase

C. glycine cleavage complex (GCC)

D. homogentisate oxidase

E. phenylalanine hydroxylase

Show Answer
Questions 3

Which of the following ratios represents the estimated likelihood that a physician will become addicted to narcotics during his/her career?

A. 1 in 10

B. 1 in 100

C. 1 in 1000

D. 1 in 10,000

E. 1 in 100,000

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USMLE USMLE-STEP-1 exam official information: Step 1 assesses whether you understand and can apply important concepts of the sciences basic to the practice of medicine, with special emphasis on principles and mechanisms underlying health, disease, and modes of therapy.